Annals of Optometry and Contact Lens 2016;15(1):28-32.
Published online March 25, 2016.
만성 골수성 백혈병과 연관하여 발생한 양안의 중심망막정맥폐쇄 1예
김미리내, 신정아, 박영훈
가톨릭대학교 의과대학 여의도성모병원 안과 및 시과학교실1,
가톨릭대학교 의과대학 성바오로병원 안과 및 시과학교실2,
가톨릭대학교 의과대학 서울성모병원 안과 및 시과학교실3
Bilateral Central Retinal Vein Occlusion Related to Chronic Myeloid Leukemia
Mirinae Kim, Jeong Ah Shin, Young Hoon Park
Department of Ophthalmology and Visual Science, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea1, Seoul, Korea
Department of Ophthalmology and Visual Science, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea2, Seoul, Korea
Department of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea3, Seoul, Korea
Received: 14 December 2015   • Revised: 18 January 2016   • Accepted: 19 January 2016
Abstract

Purpose: To report a rare case of a simultaneous bilateral central retinal vein occlusion, as the initial presentation of chronic myeloid leukemia.

Case summary: A 22-year-old man presented with conjunctival injection of both eye, decreased visual acuity of left eye, nausea and dizziness. Ophthalmic examination was consistent with non-ischemic central retinal vein occlusion of both eye. After a systemic evaluation including laboratory examinations, bone marrow biopsy, and abdomen computed tomography, he was diagnosed as chronic myeloid leukemia. The patient received massive hydration and chemotherapy with hydroxyurea, allopurinol, and torsemide. On follow-up at 2 months, his visual acuity recovered to 0.8 in right eye, and 0.63 in left eye. The ocular status has remained stable at 2 year of follow-up.

Conclusions: All ocular structures have been found to be involved in patients with leukemia, but visual impairment as the initial symptom of leukemia is rare. A prompt search for the underlying systemic disease should be performed in young patients presenting with central retinal vein occlusion.

Key Words: Hematologic neoplasms; Leukemia; Myeloid Leukemia, Chronic; Retinal vein occlusion


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