Korean Journal of Optometry and Vision Science 2011;10(1):5-11.
Published online June 20, 2011.
안허혈 증후군의 임상 양상 및 치료
양지욱, 정진, 박영훈
1Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, 2St. Mary's Eye Clinic, Uijeongbu, Korea
The Clinical Features and Managements of Ocular Ischemic Syndrome
Ji-Wook Yang, Jin Chung, Young-Hoon Park
Abstract
Purpose
To evaluate the clinical manifestations and the systemic diseases of ocular ischemic syndrome and the relationship between the stenosis of internal carotid artery and the visual prognosis. Methods: We retrospectively reviewed the medical records of 11 ocular ischemic syndrome patients. By ocular examinations including slit lamp examination and fluorescein angiography, magnetic resonance angiography, carotid artery ultrasonography and trans-femoral carotid angiogram, we investigated visual acuity, new vessels at iris, intraocular pressures, grades of cataract and stenosis of internal carotid artery. Also we investigated the persences of cerebrovascular diseas, diabetes mellitus, hypertension, ischemic heart disease and other systemic disorders. Results: The average age of 11 patients was 50.8 years old. The final visual prognosis became poorer in proportion to the stenosis of internal carotid artery (p<0.01), there were more severe grades of cataract in the eyes which had ocular ischemic syndrome compared with unaffected eyes. 4 patients (36.4%) had cerebrovascular attack, 2 patients (18.2%) ischemic heart disease, 4 patients (36.4%) diabetes mellitus and 5 patients (45.4%) hypertention. In one case which had ocular ischemic syndrome acutely, visual acuity improved 0.04 initially to 1.0 after urokinase injection through internal carotid artery. Conclusions: When the clinical symptoms of ocular ischemic syndrome were shown, the examinations into internal carotid artery should be necessary. The final visual prognosis became poorer in proportion to the stenosis of internal carotid artery and there were more severe grades of cataract in the eyes which had ocular ischemic syndrome compared with unaffected eyes. And if ophthalmologist diagnosed ocular ischemic syndrome, anticoagulant therapy through internal carotid artery could be considered. (Korean J Optom Vis Sci 2011;10(1):5-11)
Key Words: Internal carotid artery stenosis, Ocular ischemic syndrome, Visual prognosis


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