| 항정신병 약물 장기 복용 후 양안 각막 기질 색소침착 및 백내장이 발생한 2예 |
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최진아, 김수영 |
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Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea |
| Ocular Pigmentation after Long Term Use of Chlorpromazine |
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Jin A Choi, Su-Young Kim |
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| Abstract |
Purpose
To report two cases of ocular changes after long term use of chlorpromazine. Methods: Two cases were presented with decreased visual acuity after long term use of chlorpromazine due to schizophrenia. Results: They showed corneal granular pigment deposition in post. stroma, Descemet membrane and endothelium, stellate ant. subcapsular cataract involving visual axis, and also decreased corneal endothelial cell count, which were persistent, although the chlorpromazine was changed into olanzapine. Conclusions: In cases of patients taking chlorpromazine, the regular ocular examination should be considered, because ocular pigment deposition occurs according to the accumulative dosage of the medicine. (Korean J Optom Vis Sci 2010;9(2):53-57) |
| Key Words:
Chlorpromazine, Corneal deposition, Phenothiazine, Stellate cataract, Total accumulative dosage |
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