Korean Journal of Optometry and Vision Science 2008;7(1):42-45.
Published online December 20, 2008.
망막중심동맥폐쇄에 합병된 망막신생혈관의 유리체강 내 아바스틴 주입술에 의한 치험 1예
최현준, 최경섭
Department of Ophthalmology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea
A Case of Intravitreal Avastin® Injection for Retinal Neovascularization Associated with Central Retinal Artery Occlusion
Hyun Joon Choi, Kyoung Sub Choi
Abstract
Purpose
To report a case of regression of retinal neovascularization following central retinal artery occlusion with a single intravitreal injection of avastin® (bevacizumab). Methods: A 71-year-old man without significant past medical history visited our clinic because of diminished vision in his both eyes (count-finger vision). Fundus examination showed retinal opacification on the posterior pole around the center of the macula with significant reduction of the retinal circulation, but there is no cherry-red spot at the fovea. Fluorescein angiography revealed marked delay in arteriovenous transit time in both eyes, and leakage from retinal neovascularization in the right eye. Five months after the occlusion, fundus examination of the right eye showed vitreous hemorrhage and increased retinal neovascularization. We performed intravitreal avastin® injection. Results: After three weeks, there was decreased vitreous hemorrhage and regression of neovascularization on fluorescein angiography in the right eye. Conclusions: Our experience suggests that intravitreal avastin® injection may be a safe and effective alternative to conventional therapeutic procedures for retinal neovascularization with central retinal artery occlusion. (Korean J Optom Vis Sci 2008;7(1):42-45)
Key Words: Central retinal artery occlusion, Retinal neovascularization, Bevacizumab (Avastin®; )
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