Korean Journal of Optometry and Vision Science 2007;6(1):89-93.
Published online December 20, 2007.
원자 폭탄 피해자의 후손에서 발생한 색소성 건피증과 각막 편평상피세포암 1예
이동초, 최웅산, 안정현
1Yeong-Dong Good Ophthalmic Clinic, Yeongdong, 2Seoul Ophthalmic Clinic, Seoul, 3Department of Ophthalmology, Dankook University, College of Medicine, Cheonan, Korea
A Case of Corneal Squamous Cell Carcinoma and Xeroderma Pigmentosum in the Son of Atomic Bomb Survivor
Dong Cho Lee, Woong San Choi, Jung Hyun Ahn
Abstract
Purpose
To report a case of corneal squamous cell carcinoma and Xeroderma pigmentosum in the offspring of atomic bomb survivor. Methods: A 45-year old male diagnosed with Xeroderma Pigmentosum at the age of 15 years presented with decreased visual acuity of his left eye. His brother also had Xeroderma Pigmentosum. His father was atomic bomb survivor in Hiroshima. Multiple squamous cell carcinoma affected right eye which was developed on his face starting from the age of 15 years, and were treated by local excision and exentration at other hospital. On his first visit to our hospital, his left visual acuity was 0.3. The left eye revealed 3×6 mm sized, whitish mass on temporal cornea, and corneal opacity on nasal cornea with pterygium-like growth. The excision of the pterygium-like lesion and corneal mass was done. Amniotic membrane was sutured with 10-0 nylon to cover the bare sclera fully. Results: The pathologic result was consistent with the diagnosis of squamous cell carcinoma in situ. During the one year follow-up, neither recurrence nor any postoperative complication. We found postoperative best corrected visual acuity improved from 0.3 to 0.6 after one year. (Korean J Optom Vis Sci 2007;6(1):89-93)
Key Words: Amniotic membrane graft, Atomic-bomb survivor, Corneal squamous cell carcinoma, Xeroderma Pigmentosum
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