Characteristics of Optical Coherence Tomography Finding in Patients with Pituitary Adenoma

Jung, Jae Woo; Jo, Seong Ho; Seo, Je Hyun; Jung, Jae Ho; Sung, Soon Ki

Original Article

Annals of Optometry and Contact Lens 2015;14(4):189-193.
Published online December 25, 2015.

Characteristics of Optical Coherence Tomography Finding in Patients with Pituitary Adenoma

Jae Woo Jung, Seong Ho Jo, Je Hyun Seo, Jae Ho Jung, Soon Ki Sung

Department of Ophthalmology, Pusan National University Yangsan Hospital¹, Yangsan, Korea, Department of Neurosurgery, Pusan National University Yangsan Hospital², Yangsan, Korea

Received: 10 July 2015 • Revised: 19 September 2015 • Accepted: 21 September 2015

Abstract

Purpose: To assess differences in spectral-domain optical coherence tomography (OCT) parameters between who diagnosed pituitary adenoma and glaucoma.
Methods: In this study retrospectively evaluated three groups (14 eyes of 7 patients with pituitary adenoma, 14 eyes of 14 patient with glaucoma who has same visual field defect as pituitary adenoma patients, 14 eyes of 14 patients normal controls) were detected visual fiels defect and imaged with spectral-domain OCT (cup to disc ratio, regional retinal nerve fiber layer (RNFL) thickness, ganglion cell complex) between January 2013 and December 2014. In each group regional RNFL thickness.
Results: There are statistically significant differences in temporal retinal nerve fiber layer thickness between group of patients with pituitary adenoma and normal controls. And we found that there are statistically significant differences in average cup to disc ratio, vertical cup to disc ratio, cup volume between group of patients with pituitary adenoma and glaucoma (P<0.05). No other parameters in the three groups were significantly different.
Conclusions: These results indicate that optical coherence tomography finding is distinguish patients with pituitary adenoma from glaucoma.

Key Words: Optical coherence tomography, Pituitary adenoma, Retinal ganglion cell, Retinal neuron