A Case of Interdigital Skin Hyperpigmentation of the Hand Following the Use of Travoprost |
Minji Park, Sung A Lim, Man Soo Kim |
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea |
Received: 26 March 2015 • Revised: 27 May 2015 • Accepted: 29 May 2015 |
Abstract |
Purpose: To report a case of interdigital skin hyperpigmentation of the hand following the use of travoprost. Case summary: 0.004% travoprost was administered to a 57-year-old man to treat secondary glaucoma that occurred after keratoplasty in his both eyes. After 3 weeks of treatment with 0.004% travoprost. We detected the appearance of skin hyperpigmentation in both eyelids and in the interdigital skin of both hands. Thus, to establish whether 0.004% travoprost was the cause of the hyperpigmentation, we discontinued 0.004% travoprost and observed for a decrease in the amount of pigmentation. The hyperpigmentation of both eyelids and interdigital skin markedly decreased at 1 and 5 months, respectively, after the discontinuation of 0.004% travoprost. Conclusions: Eyelid hyperpigmentation is a commonly known side effect of prostaglandin analogs. The type of interdigital skin hyperpigmentation reported here is a very rare side effect of 0.004% travoprost, highlighting the importance of this first case report from Korea. Ann Optom Contact Lens 2015;14(2):115-118 |
Key Words:
Hyperpigmentation, Prostaglandine analogue, Side effect, Travatan< SUP> ® < /SUP> , Travoprost |
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