Treatment of Macular Edema Secondary to Branch Retinal Vein Occlusion

Park, Sunho; Choi, Kyung Seek

Original Article

Annals of Optometry and Contact Lens 2015;14(2):84-91.
Published online June 25, 2015.

Treatment of Macular Edema Secondary to Branch Retinal Vein Occlusion

Sunho Park, Kyung Seek Choi

Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea

Received: 16 February 2015 • Revised: 30 April 2015 • Accepted: 29 May 2015

Abstract

Purpose: To compare the effect and complications of treatments for macular edema secondary to branch retinal vein occlusion.
Methods: Literature review using the Korean medical database and the Korean Ophthalmological Society database, Korean Journal of Ophthalmology was performed. To compare the effect, studies used consisted of patients with macular edema secondary to branch retinal vein occlusion, according to visual acuity (VA) outcomes, central macular thickness (CMT) at 1, 3, and 6 months.
Results: In the three studies comparing Intravitreal Triamcinolone Acetonide (IVTA) injection with intravitreal bevacizumab (IVB) injection, IVB injection demonstrated greater improvement in CMT at 1 month. In the three studies comparing IVTA or IVB single injection with laser photocoagulation or subtenon triamcinolone acetonide (STTA) combination therapy, combination therapy demonstrated greater improvement in VA and CMT at 3 and 6 months.
Conclusions: The functional and anatomical improvements are achieved by IVTA injection, IVB injection, and combination therapy for macular edema secondary to branch retinal vein occlusion. The effect of IVB and IVTA injection is nearly similar and combination therapy is more prominent than monotherapy with longer duration.
Ann Optom Contact Lens 2015;14(2):84-91

Key Words: Bevacizumab, Branch retinal vein occlusion, Laser photocoagulation, Macular edema, Triamcinolone acetonide