| Long-term Corneal Morphological Changes after Laser in Situ Keratomileusis by Confocal Microscopy: Three Cases Reports |
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Soo Gyeong Jang, Ho Yun Kim, Young Min Park, Jong Soo Lee |
Department of Ophthalmology, Pusan National University Hospital, Pusan National University School of Medicine1, Pusan, Korea
Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine2, Yangsan, Korea |
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Received: 14 December 1901 • Revised: 9 October 2015 • Accepted: 29 October 2015 |
| Abstract |
Purpose: To report the confocal morphological changes in the cornea at least 12 months after laser in situ keratomileusis(LASIK) compared with normal cornea.
Case summary: Confocal microscopy was used to obtain data from three cases of post- LASIK at least 12 months. We evaluated confocal morphological images of the activated keratocyte, scarring tissue, stromal folding in the corneal epithelium, Bowman’s layer, stromal cells (anterior, middle, posterior keratocyte) and endothelium. Case 1) At 12 months after LASIK, although scar tissue was not observed, active keratocyte and stromal folding due to stromal edema were noted. Case 2) At 24 months after LASIK, active keratocyte and scarring tissue were not found. However, regenerated nerve plexus in the subepithelial nerve fiber layers was crooked and the stromal folding due to stromal edema was observed. Case 3) At 36 months after LASIK, the corneal epithelium and wing cell were normal but stromal folding still remained.
Conclusions: Active keratocyte and stromal folding were still noted at 12 months after LASIK. Especially, stromal folding due to stromal edema remained at 36 months after LASIK. |
| Key Words:
Confocal microscopy, Keratocyte, Laser in situ keratomileusis, Opacity |
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