| 한국인 녹내장 및 고안압증 환자에서 타플루프로스트의 안압 하강 효과 |
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경학수, 이승재 |
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국립중앙의료원 안과 |
| Intraocular Pressure Lowering Effect of Tafluprost in Korean Glaucoma andOcular Hypertension Patients |
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Haksu Kyung, Seung Jae Lee |
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Department of Ophthalmology, National Medical Center, Seoul, Korea |
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| Abstract |
Purpose
To investigate intraocular pressure (IOP) lowering effect of Tafluprost in Korean glaucoma and ocular hypertension
patients.
Methods: Seventy eight patients, one hundred thirty five eyes, diagnosed with glaucoma and ocular hypertension received
Tafluprost once daily. We analyzed IOP and its change from baseline at week 1, month 1, moth 3, month 6 and month 9.
Results: Among all 135 eyes, 117 eyes had normal tension glaucoma (NTG), 11 eyes had primary open angle glaucoma
(POAG), and 7 eyes had ocular hypertension (OHT). The average IOP was 16.0 ± 3.7 mm Hg at baseline, 12.5 ± 2.5 mm Hg
(least squares [LS] mean difference: -4.6 mm Hg; p < 0.0001) after 1 week, 12.6 ± 2.7 mm Hg (-3.2 mm Hg; p < 0.0001) after 1
month, 12.4 ± 3.0 mm Hg (-2.8 mm Hg; p < 0.0001) after 3 months, 12.8 ± 3.0 mm Hg (-3.9 mm Hg; p <0.0001) after 6 months
and 12.0 ± 2.5 mm Hg (-2.7 mm Hg; p < 0.0001) after 9 months. All measurements showed a statistically significant IOP
reduction.
Conclusions: Tafluprost was effective in IOP lowering effects up to 9 months in Korean glaucoma and ocular hypertension
patients.
(Korean J Optom Vis Sci 2014;13(1):19-23) |
| Key Words:
Glaucoma, Intraocular pressure reduction, Prostaglandin analogs, Tafluprost |
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