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Efficacy and Safety of iStent Trabecular Microbypass Stent in Open Angle Glaucoma in Korean
Ann Optom Contact Lens 2019;18:81-85
Published online September 25, 2019
© 2019 The Korean Optometry & Contact Lens Study Society

Sue Hey Chae, MD, Tae Heon Lee, MD, Kyung Heon Lee, MD, Jin Young Rhew, MD

Sungmo Eye Hospital, Busan, Korea
Correspondence to: Jin Young Rhew, MD
Sungmo Eye Hospital, #409 Haeun-daero, Haeundae-gu, Busan 48064, Korea
Tel: 82-51-743-0775, Fax: 82-51-743-0776
Received July 16, 2019; Revised August 28, 2019; Accepted September 16, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: To evaluate efficacy and safety of the iStent Trabecular Micro-Bypass stent used as the sole procedure in patients with primary open-angle glaucoma (POAG).
Methods: Retrospective, consecutive case series involving 12 Korean patients, 12 eyes with POAG that were implanted with 1 iStent trabecular micro-bypass stent. Data were collected preoperatively, and at 1, 3, and 6 months, 12 months, postoperatively. Data included intraocular pressure (IOP), visual acuity test and slit lamp examination.
Results: Mean preoperative IOP was 20.6 ± 4.4 mmHg and significantly decreased in 16.3 ± 2.5 mmHg at three months (p < 0.05), in 16.6 ± 3.6 mmHg at 12 months postoperatively (p < 0.05). The mean number of glaucoma medications was 1.83 ± 0.25 preoperatively and 1.58 ± 0.30 (p < 0.05) at 12 months postoperatively. No significant changes in visual acuity were noted. The most common complications comprised mild hyphema in 3 eyes, mild uveitis in 4 eyes and transient IOP spike in 3 eyes on postoperative day 1 and all instances were medically well controlled.
Conclusions: The significat IOP reduction after iStent insertion in Korean patients occurred after one week of operation. An IOP reduction from baseline occurred at 12 months after implantation of iStent.
Keywords : Glaucoma; Glaucoma filtration implants; iStent; Intraocular pressure

September 2019, 18 (3)