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Complete Ptosis Caused by Ocular Adnexal Involvement of Non-Hodgkin lymphoma: A Case Report
Ann Optom Contact Lens 2018;17:10-13
Published online March 25, 2018
© 2018 The Korean Optometry & Contact Lens Study Society

Hae Rang Kim, MD1, Bomi Kim, MD, PhD2, Soo Jung Lee, MD, PhD1

Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine1, Busan, Korea
Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine2, Busan, Korea
Correspondence to: Soo Jung Lee, MD, PhD
Department of of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, #875 Haeundae-ro, Haeundae-gu, Busan 48108, Korea
Tel: 82-51-797-2311, Fax: 82-51-797-2314
Received December 6, 2017; Revised January 9, 2018; Accepted January 11, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: Orbital and ocular adnexal lymphoma is a very rare disease, which can present with various neurological symptoms and visual disturbances. We report a case of complete ptosis as the first clinical presentation of recurrence in Non-hodgkin lymphoma patient who sustained complete remission.
Case summary: A 82-year-old man presented with progressive swelling and palpable mass in the left upper eyelid. Complete ptosis of the left eye was noted. When the left upper eyelid was lifted manually, the patient complained of vertical diplopia. Left hypotropia of 8 prism diopters and -1 limitation of upgaze in the left eye were observed. He had sustained complete remission after the completion of the 7th chemotherapy for Non-hodgkin lymphoma 21 months ago. A homogeneous crescentric mass on the left upper eyelid was confirmed on orbit magnetic resonance imaging. The pathology confirmed diffuse large B-cell lymphoma. After chemotherapy, the mass disappeared on the radiologic test. Resolution of diplopia and left hypotropia were observed even though there was no improvement in ptosis of the left eye.
Conclusions: Complete ptosis could be a rare clinical presentation of Non-hodgkin lymphoma. Thus, it should be regarded as one of the differential diagnosis for ptosis.
Keywords : Complete blepharoptosis; Diffuse large B-cell lymphoma; Non-hodgkin lymphoma; Orbital lymphoma

December 2018, 17 (4)